Pyridazines and derivatives
Apexbio Technology LLC Phthalazinone pyrazole 880487-62-7 1mg
Phthalazinone pyrazole (CAS 880487-62-7) is a potent selective and orally bioavailable inhibitor of Aurora-A kinase a member of the Aurora kinase family that regulates key processes in cell division Dysregulation of Aurora-A is linked to chromosomal instability and oncogenesis in various tumor types In vitro phthalazinone pyrazole demonstrates strong inhibition of Aurora-A kinase activity with an IC50 of 31 nM while showing minimal effect on Aurora-B kinase at concentrations up to 100 M It inhibits the proliferation of HCT116 Colo205 and MCF-7 cells with IC50 values of 7 8 2 9 and 1 6 M respectively This compound is utilized in research to investigate the role of Aurora-A in cell cycle regulation and cancer biology
Sigma Aldrich Fine Chemicals Biosciences Luminol >=97% (HPLC) | 521-31-3 | MFCD00006890 | 25G
Luminol >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 177.16 | 521-31-3 | MFCD00006890 | 25G
Sigma Aldrich Fine Chemicals Biosciences Luminol | 521-31-3 | MFCD00006890 | 5g
Luminol | Purity: 97% | Mol Wt: 177.16521-31-3 | MFCD00006890 | 5g
Chemscene ChemScene | 6-Chloropyridazine-3-carbaldehyde | 250MG | CS-0019042 | 0.98 | 303085-53-2| MFCD10698041 | 142.54
ChemScene | 6-Chloropyridazine-3-carbaldehyde | 250MG | CS-0019042 | 0.98 | 303085-53-2| MFCD10698041 | 142.54
![eMolecules 3-BROMOTHIENO[2,3-D]PYRIDAZIN-4(5H)-ONE | 1433203-93-0 | MFCD28129629 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502182183.JPG-250.jpg)
eMolecules 3-BROMOTHIENO[2,3-D]PYRIDAZIN-4(5H)-ONE | 1433203-93-0 | MFCD28129629 | 1g
AstaTech | 3-BROMOTHIENO[2,3-D]PYRIDAZIN-4(5H)-ONE | 1g | 624127180 | 73488 | 95.000 | 1433203-93-0 | MFCD28129629 | 231.070 | C6H3BrN2OS
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eMolecules 1,6-dihydro-6-oxo-4-pyridazinecarboxylic acid methyl ester | 89640-81-3 | | 5g
WuXi ChemSupply | 1,6-dihydro-6-oxo-4-pyridazinecarboxylic acid methyl ester | 5g | 599169765 | LN02161681 | 95.000 | 89640-81-3 | | 154.125 | C6H6N2O3
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eMolecules 3-chloro-4-ethyl-1H-pyridazin-6-one | 61404-44-2 | MFCD22380842 | 1g
Pharmablock | 3-chloro-4-ethyl-1H-pyridazin-6-one | 1g | 551162671 | PBU4569 | | 61404-44-2 | MFCD22380842 | 158.590 | C6H7ClN2O
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eMolecules Pharmablock pyridazin-3-ylmethanol 50mg 551187448 PB00385 0 000 37444-46-5 MFCD04972629 110 116 C5H6N2O
Pharmablock pyridazin-3-ylmethanol 50mg 551187448 PB00385 0 000 37444-46-5 MFCD04972629 110 116 C5H6N2O
eMolecules 6-Chloro-phthalazin-1-ol | 57835-96-8 | MFCD13190052 | 1g
J & W PharmLab, LLC | 6-Chloro-phthalazin-1-ol | 1g | 249992004 | 70R0191 | 96.000 | 57835-96-8 | MFCD13190052 | 180.590 | C8H5ClN2O
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eMolecules Key Organics/BIONET 3-Aminopyridazine 1mg 564171106 PS-9352 95 000 5469-70-5 MFCD01529869 95 105 C4H5N3
Key Organics/BIONET 3-Aminopyridazine 1mg 564171106 PS-9352 95 000 5469-70-5 MFCD01529869 95 105 C4H5N3
eMolecules Pharmablock pyridazin-3-ylmethanol 250mg 551056238 PB00385 0 000 37444-46-5 MFCD04972629 110 116 C5H6N2O
Pharmablock pyridazin-3-ylmethanol 250mg 551056238 PB00385 0 000 37444-46-5 MFCD04972629 110 116 C5H6N2O